منابع مشابه
Genetic Code: What Nature Missed
The genetic code encodes 20 amino acids in almost all living cells; the only known exceptions are a few organisms that use selenocysteine [1] or pirrolysine [2]. In order to acquire chemical properties not represented in this set, proteins must be modified post-translationally, be made non-ribosomally, or use co-factors. In a series of papers, Peter Schultz’s group has described how they carrie...
متن کاملWhat Froze the Genetic Code?
The frozen accident theory of the Genetic Code was a proposal by Francis Crick that attempted to explain the universal nature of the Genetic Code and the fact that it only contains information for twenty amino acids. Fifty years later, it is clear that variations to the universal Genetic Code exist in nature and that translation is not limited to twenty amino acids. However, given the astonishi...
متن کاملGeneral Nature of the Genetic Code for Proteins
HERE is now a mass of indirect evidence which suggests that ths amino-a&d sequence along the polypeptids chain of a protein is determined by the sequence of the bases along some particular part of the nucleic acid of the genetic material. Since there are twenty common amino-acids found throughout Sature, but only four common bases, it haa often been surmised that the sequence of the four baaes ...
متن کاملEstablishing the Triplet Nature of the Genetic Code
In 1961, Crick, Barnett, Brenner, and Watts-Tobin (Crick et al., 1961) designed an elegant experimental strategy to determine the nature of the genetic code. Remarkably, they reached the correct conclusion despite the absence of technology to analyze and compare DNA and protein sequences.
متن کاملGenetic code
Is the code universal? No. Although most organisms have the same genetic code, researchers began to discover exceptions to the ‘universal’ code in 1979, and today we know of more than 15 alternative codes; each has just a few differences from the standard code, indicating common ancestry from this code. Several of these codes arose independently a number of times in evolution and are present in...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2003
ISSN: 0960-9822
DOI: 10.1016/j.cub.2003.10.052